The effect of intrauterine growth on mental and psychomoter development in one-year-old discordant twins infants
XIANG Huiqiu1, HUANG Xianping1, JIN Jiaxi1, SHAO Haoran2, CHI Meizhu2, LIN Feng3, XU Zhangye1.
1.Department of Obstetrics, the Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325027; 2.Department of Pediatrics, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325015; 3.Department of Obstetrics, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325015
XIANG Huiqiu,HUANG Xianping,JIN Jiaxi, et al. The effect of intrauterine growth on mental and psychomoter development in one-year-old discordant twins infants[J]. JOURNAL OF WEZHOU MEDICAL UNIVERSITY, 2016, 46(2): 84-87.
Abstract：Objective: To assess the effect of intrauterine growth on mental and psychomoter development in one-year-old discordant twins infants. Methods: Total of 34 discordant twin pregnancies (68 one-year-old discordant twins infants) with complete delivery records in Obstetrics department of the First and Second Affiliated Hospital of Wenzhou Medical University from January 2012 to December 2013 were followed-up. According to the discordant birthweight, each pair infant was divided into small weight group and large weight group. Weight, length, head circumferences, the mental developmental index (MDI) and psychomotor developmental index (PDI) were measured. Results: Small weight group was lower than that of large group at length, weight and head circumstance (P<0.05); PDI but not MDI was significantly different between two groups (P<0.05). Psychomotor retardation rates (PDI<70) were 17.6% in small weight group while 2.9% in large weight group (P<0.05). Stepwise regression analysis showed that the influence of height and weight of PDI had significant statistical significance (P<0.05). Conclusion: Intrauterine fetal growth and development leads to twins after birth weight differences, and sustained impact to born after 1 year old children’s height, weight and head circumference of physical growth and psychomotor development.
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