Epidemiological investigations of perioperative risk factors for early death in newborns and infants
KONG Weiwei1, WANG Xiaoqing1, WANG Zhongsu1, WAN Mengjiao1, XIE Kangjie2, XIE Zuokai1, SHANGGUAN Wangning1, LIAN Qingquan1, LI Jun1.
1.Department of Anesthsiology, the Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325027; 2.Department of Anesthsiology, Zhejiang Cancer Hospital,Hanzhou, 310022
KONG Weiwei1,WANG Xiaoqing,WANG Zhongsu, et al. Epidemiological investigations of perioperative risk factors for early death in newborns and infants[J]. JOURNAL OF WEZHOU MEDICAL UNIVERSITY, 2016, 46(1): 44-47.
Abstract：Objective: To analyze clinical epidemiological characteristics with perioperative death associated risk factors of children under 1 year of age in the early period (less than 3 days). Methods: The clinical data from 76 cases of neonates and infants dead during perioperation from January 2011 to December 2013 were investigated in the Second Affiliated Hospital of Wenzhou Medical University. Retrospective analysis were conducted on their gender, gestational age, onset age, birth weight, preoperative weight, preoperative complications (such as cardiovascular disease, respiratory diseases, blood disorders, liver and kidney disease), preoperative conscious state, electrolyte imbalance or not, the malnutrition or not, ASA classification, site of surgery, type of surgery, duration of surgery and operation classification. Results: Spearman rank correlation analysis was performed respectively among birth weight, preoperative respiratory disease, ASA classification grade and preoperative state of consciousness with death in early time. P value was lower than 0.05, according to P<0.05 statistical standards, it had statistical significance. All the four risk fators above-mentioned entered into Logistic stepwise regression analysis, and finally only two risk factors (preoperative respiratory diseases and ASA classification)were reserved. From the area under the RoC curve analysis that neonates and infants during perioperative period of early (less than 3 days) time of death risk factors were highly correlated in preoperative respiratory disease(0.643), ASA classification (0.694). Conclusion: Preoperative respiratory disease and ASA classification are the effective predictor of perioperative early death in neonates and infants, and predictive value of ASA classification was stronger.
