Investigation for distribution of the patient suffered with cognitive disorder and the compliance of those patients at memory clinic of neurology
1.The First Department of Neurology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325015; 2.Department of Rehabilitation, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325015; 3.Department of Psychiatry, the First Affiliated Hospital of Yangtze University, Jingzhou, 434000
Abstract:Objective: To observe the distribution of the outpatients suffered with cognitive disorder at memory clinic of neurology in our hospital. To find the factors which effected on the compliance of those patients. Methods: Consecutive cases of outpatients complaining with cognitive disorder at neurology clinic were collected from Nov. 2012 to Jan. 2013, the different causes for cognitive disorder of patients were definited and the degree of severity was described.2. Prospective following-up: all the cases were followed up to 56±7 days after registration, the factors with effected on the compliance of the patients were collected, non-conditional logistic regressions analysis was adopted as statistical method. Results: Total 93 cases complaining with memory disorder were screened, 60 patients with cognitive disorder were chosen, among them there were 40 cases of Alzheimer’s disease (AD) type, with the percent of 66.67%, 7 cases with cognitive impairment of vascular type, 2 cases of frontotemporal dementia (FTD), and 11 cases of other causes. Account to the degree of the severity, there were 11 cases with mild cognitive impairment (MCI), the percent was 18.33% and the cases of middle-severe patient were 34, the percent was 57%. By the study of the 8 possible factors, it showed that the degree of education was the independent factor (P=0.01, OR=2.3, 95%CI: 1.19~4.45) for the compliance of those patients. Conclusion: Cognitive impairment of AD type is the first cause of the patients with cognitive disorder at our memory clinic, middle-severe cognitive disorder patients take a high percent, the degree of education is the independent factor for compliance of the patients.
[1] 贾建平, 王荫华, 李焰生, 等. 中国痴呆与认知障碍诊治指南(二): 痴呆的分型及诊断标准[J]. 中华医学杂志, 2011,91(10): 651-654.
[2] Zhang ZX, Zahner GE, Román GC, et al. Socio-demographic variation of dementia subtypes in china: Methodology and results of a prevalence, study in Beijing, Chengdu, Shanghai, and Xi, an[J]. Neuroepidemiology, 2006, 27(4): 177-187.
[3] 于大林, 吕建为, 易刚, 等. 神经内科门诊痴呆的流行病学调查[J]. 中华临床医师杂志, 2013, 7(8): 3404-3407.
[4] 夏叶子, 麻小莉, 尉晓娜, 等. 神经内科门诊患者认知障碍的横断面调查[J]. 医学研究杂志, 2011, 40(3): 58-60, 82.
[5] 丁玎, 洪震. 老年性痴呆和轻度认知功能障碍的流行病学研究进展[J]. 中国临床神经科学, 2013, 21(1): 101-108.
[6] Roberts RO1, Knopman DS, Mielke MM, et a1. Higher risk of progression to dementiain mild cognitive impairment cases who revert to normal[J]. Neurology, 2014, 82(4): 317-325.
[7] 刘爽, 张玉莲, 周震, 等. 老年性痴呆流行病学研究现况[J].中国老年学杂志, 2010, 30(10): 1455-1457.
[8] Zhou DF, Wu CS, Qi H, et a1. Prevalence of dementia in rural China: impact of age,gender and education[J]. Acta Neurol Scand, 2006, 114(4): 273-280.
[9] Dhikav V1, Singh P, Anand KS, et a1. Medication adherence survey of drugs useful in prevention of dementia of Alzheimer’s type among Indian patients[J]. Int Psychogeriatr, 2013, 25(9): 1409-1413.
[10] Gardette V, Lapeyre-Mestre M, Piau A, et a1. A 2-year prospective cohort study of antidementia drug non-persistency in mild-to-moderate Alzheimer’s disease in Europe[J]. CNS Drugs, 2014 , 28(2): 157-170.