The correlative analysis analysis between thyroid-stimulating hormone levels and metabolic syndrome during pregnancy
1.Department of Obstetrics and Gynecology, the Third Affiliated Clinical College of Wenzhou Medical University, Wenzhou People’s Hospital, Wenzhou, 325000; 2.Department of Obstetrics and Gynecology, the Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325027
ZHOU Qingdiao1,ZHENG Xiaodong1,LI Xiumei1, et al. The correlative analysis analysis between thyroid-stimulating hormone levels and metabolic syndrome during pregnancy[J]. JOURNAL OF WEZHOU MEDICAL UNIVERSITY, 2015, 45(10 ): 758-.
Abstract：Objective: To investigate the relationship between thyroid-stimulating hormone (TSH) levels and metabolic syndrome during pregnancy. Methods: Nine hundred and eleven single pregnant women who accepted regular obstetrical inspection and delivered in Wenzhou People’s Hospital were enrolled. One hundred and forty-nine cases with subclinical hypothyroidism (TSH>3.0 mIU/L) were divided into study group and other 762 pregnant women with TSH<3.0 mIU/L were as controls. Information Including age, gestational weeks, body weight before pregnancy and biochemical indicators, including total cholesterol (CHOL), triglyceride (TG), high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C) and thyroid-stimulating hormone levels were recorded. The levels of serum lipid, the prevalence of pregnancy induced hypertension, gestational diabetes mellitus and pregnancy metabolic syndrome were compared between the two group. Results: The levels of triglyceride in the subclinical hypothyroidism group were much higher than that in the controls. The difference was statistically significant (P<0.05). The incidence of GMS and pregnancy induced hypertension was much higher than that in the controls. There was no correlation between TSH and GMS (P>0.05). The TSH seemed to have relationship in the morbidity between pregnancy induced hypertension and normal (P<0.05). Conclusion: There is a significant correlation between TSH levels and triglyceride and pregnancy induced hypertension.The levels of TSH is also associated with pregnancy hypertension, but not related to GMS.
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