LIAO Shiyu,YE Yufeng,YE Jianxiao, et al. Maternal exposure factors related with children’s allergic rhinitis during pregnancy[J]. JOURNAL OF WEZHOU MEDICAL UNIVERSITY, 2015, 45(7): 493-.
Abstract：Objective: To find the relativities between children’s allergic rhinitis and their mothers’ exposure factors during pregnancy. Methods: A number of 1 260 cases of 4 to 12-year-old allergic rhinitis outpatients confirmed by skin prick test from January 2012 to December 2013 and a control group of 927 cases were enrolled. A questionnaire survey was conducted among their mothers, to evaluate the environmental exposure, structure of diet and nutrition and infection condition during pregnancy for each of them. Results: The occurrences of allergic rhinitis were closely related to maternal exposure factors during pregnancy like pet keeping (OR: 2.271, 95%CI: 1.225-4.212), passive smoking (OR: 2.518, 95%CI: 1.792-3.538), infection (OR: 3.656, 95%CI: 2.301-5.811), occasional supplement of vitamin E (OR: 0.452, 95%CI: 0.301-0.678), sufficient supplement of vitamin E (OR: 0.337, 95%CI: 0.225-0.505) and consumption of vegetable oil (OR: 0.608, 95%CI: 0428-0.863). Conclusion: Children’s allergic rhinitis is relevant with maternal exposure factors during pregnancy such as diet, environment and infection. The prevention of allergic rhinitis should begin from the pregnant period, so as to achieve the goal of primary prevention.
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