ZHENG Yongfei,WEI Peiying,KONG Jianguo, et al. Application of quantitative analysis of thoracic CT in the diagnosis of severe acute pancreatitis complicated with lung injury[J]. JOURNAL OF WEZHOU MEDICAL UNIVERSITY, 2015, 45(4): 265-.
Abstract:Objective: To explore the early diagnostic value of quantitative index of thoracic CT in severe acute pancreatitis complicated with ALI/ARDS. Methods: Sixty-nine cases of severe acute pancreatitis were collected, 34 cases complicated with ALI/ARDS. The thickness of bilateral lung consolidation, pleural fluid and thoracic cavity were measured and the ratio of them on CT mediastinal window was calculated, respectively, and then evaluate their diagnostic value for ALI/ARDS. Results: There were statistical significance of difference between SAP complicated with ALI/ARDS and SAP upon every quantitative index (the thickness ratio of left lung consolidation to thoracic cavity, the thickness ratio of left lung consolidation to pleural fluid, the thickness ratio of left pleural fluid to thoracic cavity, the thickness ratio of right lung consolidation to thoracic cavity, the thickness ratio of right lung consolidation to pleural fluid and the thickness ratio of right pleural fluid to thoracic cavity). ROC curve showed that three indexes (the thickness ratio of left lung consolidation to thoracic cavity, the thickness ratio of left lung consolidation to pleural fluid and the thickness ratio of consolidation of right lung to thoracic cavity, with positive likelihood ratio of 5.158, 3.970 and 3.530) had greater diagnostical value for SAP complicated with ALI/ARDS than others. With these three indexes, the sensitivity was 0.994 by parallel test. Conclusion: Quantitative indexes of thoracic CT have important reference for early diagnosis of SAP complicated with ALI/ARDS and can provide proof for early therapy.