The correlation between endometriosis and placenta previa in assisted reproductive technology
1.Department of Obstetrics and Gynecology, People’s Hospital of Pan’an County, Jinhua, 322300; 2.Department of Gynecology, Women’s Hospital, School of Medicine, Zhejiang University, Hangzhou, 310006
FU Xiujuan,ZHOU Yong,JIN Hangmei.. The correlation between endometriosis and placenta previa in assisted reproductive technology[J]. JOURNAL OF WEZHOU MEDICAL UNIVERSITY, 2015, 45(3): 197-.
Abstract:Objective: To investigate placenta previa associated with endometriosis in assisted reproductive technology. Methods: Consecutive 2 060 pregnancies conceived by assisted reproductive technology were recruited between 2008 and 2012 in Women’s Hospital, School of Medicine, Zhejiang University. The risk of placenta previa after assisted fertilization was analyzed. Relation of nine variables was examined, i.e. maternal age, BMI, gravidity, parity, previous abortion, previous cesarean delivery, endometriosis, ovulatory disorder, and male infertility, to placenta previa by logistic regression analysis. The correlation between endometriosis severity with placenta previa was analyzed by the nonparametric test of Spearman correlation analysis. Results: In 110 women with placenta previa, there were 69 cases complicated with endometriosis. We found that endometriosis (odds ratio=19.7; 95% CI=0.5-300.6) were significantly associated with placenta previa. Endometriosis was more serious more prone to placenta previa (the Kendall correlation coefficient is 0.274, Spearman correlation coefficient is 0.281, all P<0.001). Conclusion: Our findings suggest that endometriosis is associated with an increased risk of placenta previa in assisted reproductive technology. The higher degree of endometriosis, the more possible of placenta previa.