LI Shaotang,JIANG Feizhao,ZHU Hengliang, et al. The clinical value of prophylactic antibiotics application under the guidance of procalcitonion in intestinal obstruction[J]. JOURNAL OF WEZHOU MEDICAL UNIVERSITY, 2014, 44(5): 367-.
Abstract:Objective: To explore the clinical value of prophylactic antibiotics application under the guidance of procalcitonion in intestinal obstruction. Methods: The results of prophylactic antibiotics application were observed and analyzed in 80 cases of non-surgical treatment of intestinal obstruction. Procalcitonion and blood routine were tested in all cases in 1, 3, 5 day after admission such as cut point for research. Forty patients (experimental group) stopped using antibiotics under the normal level of procalcitonion (<0.5 ng/mL). The rest of 40 patients (control group) stopped using antibiotics on the basis of traditional standard. Results: There was no significant difference between two groups in cure time and infection complications (P>0.05); there was very significant difference between two groups in average duration of antibiotics application, the experimental group was significantly shorter than that of the control group (P<0.01). Conclusion: Prophylactic antibiotics application under the guidance of procalcitonion is superior to the traditional standard in intestinal obstruction patients.