Characteristics of short-wavelength and near-infrared fundus autofluorescence imaging in flat irregular pigment epithelial detachment in central serous chorioretinopathy
YANG Chun, ZHOU Tingye, LIN Bing.
Department of Retinal, Eye Hospital of Wenzhou Medical University, Wenzhou 325000, China
YANG Chun,ZHOU Tingye,LIN Bing.. Characteristics of short-wavelength and near-infrared fundus autofluorescence imaging in flat irregular pigment epithelial detachment in central serous chorioretinopathy[J]. JOURNAL OF WEZHOU MEDICAL UNIVERSITY, 2023, 53(12): 963-968.
Abstract：Objective: To observe the short-wavelength fundus autofluorescence (SW-FAF) and nearinfrared fundus autofluorescence (NIR-FAF) image characteristics of flat irregular pigment epithelial detachment (FIPED) in central serous chorioretinopathy (CSCR). Methods: A total of 38 eyes from 38 patients diagnosed with chronic or recurrent CSCR with FIPED at the Department of Retinal, Wenzhou Medical University Eye Hospital, between March 2020 and March 2021, were included for the retrospective study. SW-FAF, NIRFAF,and other multimodal imaging examinations were performed using the Heidelberg Spectralis HRA+OCT system to analyze the FAF characteristics of FIPED. Results: Of 38 eyes with chronic or recurrent CSCR, 20 eyes had vascularized FIPED and 18 eyes had non-vascularized FIPED. Vascularized FIPED showed punctate hypoautofluoresence (65%, 13/20), mixed hypoautofluoresence (20%, 4/20), and punctate mixed autofluorescence (15%, 3/20) on SW-FAF. Non-vascularized FIPED exhibited punctate mixed autofluorescence (55.6%, 10/18),punctate hypoautofluoresence (38.9%, 7/18), and mixed hypoautofluoresence (5.6%, 1/18) on SW-FAF.Vascularized FIPED showed fused with punctate hypoautofluoresence (80%, 16/20) and patchy mixed autofluorescence (20%, 4/20) on NIR-FAF. Non-vascularized FIPED demonstrated patchy mixed autofluorescence (83.3%, 15/18) and patchy hypoautofluoresence (16.7%, 3/18) on NIR-FAF. Conclusion: Vascularized and nonvascularized FIPED in patients with chronic or recurrent CSCR exhibit characteristic SW-FAF and NIR-FAF changes, which can guide treatment and follow-up.
