Application of personalized 10-second mass injection combined with the contrast agent dual-flow technique in synchronous imaging of axillary artery and venous CT angiography
GUO Xianzhong, DENG Qingshan,CAO Guoquan, LIU Jinjin, WANG Zhenzhang
Department of Radiology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325015, China
GUO Xianzhong,DENG Qingshan,CAO Guoquan, et al. Application of personalized 10-second mass injection combined with the contrast agent dual-flow technique in synchronous imaging of axillary artery and venous CT angiography[J]. JOURNAL OF WEZHOU MEDICAL UNIVERSITY, 2022, 52(11): 914-918.
Abstract：Objective: To investigate the effect of personalized 10-second mass injection combined with contrast agent dual-flow technique on image quality and radiation dose of CT angiography (CTA) synchronous imaging in left axillary vein and artery. Methods: Eighty-three patients who underwent CTA synchronous imaging examination of left axillary artery and vein were included in this study. They were randomly divided into group A and group B according to different contrast agent injection methods. In group A, contrast agent was injected through the right elbow vein and diluent agent was injected into the left elbow vein, while in group B unilateral cubital vein multi-stage dual-flow injection was given, with personalized injection velocity and tube voltage were set according to their body weight. Contrast agent was injected through the left cubital vein for 10 s, and then the contrast agent was diluted by double-flow technique for 15 s. The dosage of contrast agent, radiation dose,objective evaluation indexes [including CT value of axillary artery and vein, signal to noise ratio (SNR), contrast noise ratio (CNR)] and subjective score were compared between the two groups. Results: The dosage of contrast agent in group B was (28.81±5.56) mL, lower than that in group A (60 mL) (t=29.620, P<0.05). The effective radiation dose of group B was significantly lower than that of group A [(2.39±1.12) mSv vs. (3.88±0.48) mSv,t=8.330, P<0.05). There was no significant difference in subjective scores between the two groups (P>0.05). The CT values of axillary artery in group A and group B were (376.35±72.49) Hu and (348.35±67.65) Hu, respectively (P>0.05). The SNR and CNR of axillary artery were statistically different between group A and group B (39.19±14.24 vs. 25.51±13.65, t=4.391, P<0.05 for SNR; and 29.59±11.73 vs. 19.34±10.95, t=4.056, P<0.05 for CNR).The CT value of axillary vein in group B [(690.70±105.24) Hu] was significantly higher than that in group A [(490.60±95.71) Hu], and the difference was statistically significant (t=-8.783, P<0.05). The SNR and CNR of axillary vein in group A and group B were not significantly different (P>0.05). Conclusion: Synchronous axillary artery and vein imaging can be achieved with high quality by using 10-second mass injection combined with dual-flow contrast agent technology. Personalized contrast agent flow rate and tube voltage settings not only effectively ensure the image quality, but also effectively reduce the amount of contrast agent and radiation dose in this examination.
