ZHOU Haisu,ZHOU Hongwei,LI Xueping, et al. Intervention effect of written expression on reproductive stress and negative emotions in female patients with recurrent implantation failure[J]. JOURNAL OF WEZHOU MEDICAL UNIVERSITY, 2022, 52(11): 903-908.
Abstract：Objective: To explore the effect of written expression on reproductive stress and negative emotions in female patients with recurrent embryo transfer failure (RIF). Methods: A total of 213 female patients with RIF who were for treatment in Reproductive Medicine Center of the First Affiliated Hospital of Wenzhou Medical University from January 2021 to April 2022 were included. They were allocated into the observation group (n=105) and the control group (n=108) according to the odd and even number of medical record number.The control group received routine assisted reproductive health education, while the observation group was given additional written expression intervention. The anxiety, reproductive stress and patient satisfaction were compared between the two groups before and after intervention. Assessment of the correlation between the observed scores was made and the factors associated with patient satisfaction were analyzed. Results: There were no significant differences in age, years of infertility, educational level, number of embryo transfer between the two groups, and the scores of self-rating anxiety scale (SAS) and fertility problem inventory (FPI) in the observation group were significantly lower than the control group (P<0.05) while the patient satisfaction was significantly higher in observation group (P<0.05). The degree of anxiety that changed before and after intervention was positively correlated with the change degree of reproductive stress in both groups (r=0.192, P=0.005). The SAS score changes (OR=0.895, 95%CI=0.821-0.975, P=0.011) and written expression intervention (OR=0.201,95%CI=0.041-0.983, P=0.048) had statistically significant impact on patient satisfaction. Conclusion: Written expression can reduce reproductive stress and improve patient satisfaction of female patients with RIF by releasing negative emotions such as anxiety and depression.
