Incidence of deep venous thrombosis after intracerebral hemorrhage in the middle-aged and elderly and its influencing factors
CHEN Xiufang1, SUN Zifen2, WANG Xiaoxue1, DONG Xiaochen3, HU Pinglang4,HONG Xianchai4, CHEN Chan1, WANG Hongxia5
1.Department of Geriatrics, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325015, China; 2.General Ward, the Second Affiliated Hospital of Wenzhou Medical University, Wenzhou 325027, China; 3.Intensive Care Unit, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325015, China; 4.Department of Neurology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325015, China; 5.Department of Nursing, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325015, China
CHEN Xiufang,SUN Zifen,WANG Xiaoxue, et al. Incidence of deep venous thrombosis after intracerebral hemorrhage in the middle-aged and elderly and its influencing factors[J]. JOURNAL OF WEZHOU MEDICAL UNIVERSITY, 2022, 52(8): 652-656.
Abstract：Objective: To investigate the incidence of acute deep vein thrombosis (DVT) after intracerebral hemorrhage in the middle-aged and elderly and explore its influencing factors, so as to provide reference for the prevention and nursing care. Methods: A total of 245 patients with cerebral hemorrhage hospitalized within 24 hours of onset in the First Affiliated Hospital of Wenzhou Medical University from September 2019 to May 2021 were selected. All patients underwent venous ultrasound examination of lower extremities 10-14 days after onset.The prevalence of DVT in the acute stage after cerebral hemorrhage was calculated. The influencing factors of DVT after intracerebral hemorrhage in middle-aged and elderly patients were analyzed by univariate analysis and binary logistic regression analysis. Results: Of 245 middle-aged and elder patients with intracerebral hemorrhage investigated, 79 cases had DVT, with the incidence rate of 32.24%, of which 39 cases (49.37%) had no clinical symptoms of DVT. Binary logistic analysis showed that age ≥70 years old (OR=1.73, 95%CI=1.12-2.98),NIHSS score of lower limbs score ≥3 points (OR=4.13, 95%CI=2.15-8.97), continuous bed time ≥3 days (OR=4.73, 95%CI=2.25-9.78), Wells ≥2 points (OR=3.54, 95%CI=1.62-6.67), and high D-dimer at admission (OR=3.06, 95%CI=1.01-3.49) were independent risk factors for DVT in the acute stage after cerebral hemorrhage.Early rehabilitation was a protective factor for DVT (OR=0.55, 95%CI=0.28-0.96). Conclusion: The incidence of DVT after intracerebral hemorrhage was high in the middle-aged and elderly, and nearly half of patients do not have clinical symptoms of DVT. Many independent risk factors are involved in DVT of the middle-aged and elderly patients with acute stroke. Timely monitor and intervention are suggested for patients with risk factors and early rehabilitation treatment of cerebral hemorrhage should be combined to reduce the occurrence of DVT.
