Performance of MRI LI-RADS v2018 vs. CEUS LI-RADS v2017 in the diagnosis of hepatocellular carcinoma: a comparative analysis
LI Fang1, QI Xinwang2, TANG Liyu2, LIU Yeding2, XIAO Yangrui3, CHEN Xiao3, WANG Zufei3, ZHANG Kun1, LI Bingrong3
1.Department of Hepatobiliary Surgery, Central Hospital of Lishui City, Lishui 323000, China; 2.Department of Ultrasound, Central Hospital of Lishui City, Lishui 323000,
China; 3.Department of Radiology, Central Hospital of Lishui City, Key Laboratory of Imaging Diagnosis and Minimally Invasive Intervention Research of Zhejiang Province, Lishui 323000, China
LI Fang,QI Xinwang,TANG Liyu, et al. Performance of MRI LI-RADS v2018 vs. CEUS LI-RADS v2017 in the diagnosis of hepatocellular carcinoma: a comparative analysis[J]. JOURNAL OF WEZHOU MEDICAL UNIVERSITY, 2022, 52(3): 210-215,221.
Abstract：Objective: To compare the difference between magnetic resonance imaging (MRI) Liver Imaging Reporting and Data System (LI-RADS) version 2018 and contrast-enhanced ultrasound (CEUS) LI-RADS version 2017 in diagnostic efficacy for hepatocellular carcinoma (HCC). Methods: We prospectively collected the data of 153 high-risk patients (173 lesions) with HCC from August 2019 to July 2021 in Lishui Central Hospital of Zhejiang Province, and evaluated the imaging characteristics of all intrahepatic lesions. Moreover, the classifications of all intrahepatic lesions by MRI LI-RADS v2018 and CEUS LI-RADS v2017 were obtained.Based on the pathological or clinical diagnosis, all lesions were divided as HCC group (119 cases), other malignancy (OM) group (20 cases) and benign lesion group (34 cases). The sensitivity, specificity and accuracy of MRI LI-RADS v2018 and CEUS LI-RADS v2017 for the diagnosis of HCC or OM were calculated. The Mann-whitney U test was used to compare the classification results between MRI LI-RADS v2018 and CEUS LI-RADS v2017. Results: Regarding the classification results of HCC or OM, there was no statistical differencebetween MRI LI-RADS v2018 and CEUS LI-RADS v2017 (Z=-0.363, -1.705; P=0.717, 0.088). In applications of MRI LI-RADS v2018 and CEUS LI-RADS v2017, the LR-5 criterion for the diagnosis of HCC had respective sensitivity of 63.9% and 63.9%, specificity of 98.1% and 92.6%, accuracy of 74.6% and 72.8%. The joint criterion of LR-4 and LR-5 for the diagnosis of HCC showed respective sensitivity of 74.8% and 84.9%, specificity of 94.4% and 70.4%, accuracy of 80.9% and 80.3%. Besides, the LR-M criterion for the diagnosis of OM showed respective sensitivity of 90.0% and 70.0%, specificity of 87.6% and 90.8%, accuracy of 87.9% and 88.4%.Among all, the MR v2018 result was significantly higher than the CEUS v2017 in regarding the specificity of LR-4/5 criteria for the diagnosis of HCC, showing statistical difference (P=0.001). Conclusion: Both the LR-5 and LR-M criteria of MRI LI-RADS v2018 and CEUS LI-RADS v2017 have similar diagnostic efficacy for HCC
and OM, with MR v2018 significantly higher than that of the CEUS v2017 in comparison of the specificity by LR-4/5 criteria for the diagnosis of HCC.
