Three different sites of phosphaturic mesenchymal tumor: a clinicopathologic analysis
SONG Chunhong1, WU Liang2, YIN Weiwei3, WANG Rongrong2
1.Department of Pathology, Aksu First People’s Hospital, Aksu 843000, China; 2.Department of Pathology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325015, China; 3.Department of Nuclear Medicine, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325015, China
SONG Chunhong,WU Liang,YIN Weiwei, et al. Three different sites of phosphaturic mesenchymal tumor: a clinicopathologic analysis[J]. JOURNAL OF WEZHOU MEDICAL UNIVERSITY, 2022, 52(2): 153-157.
Abstract：Objective: To study the clinicopathological features of the phosphaturic mesenchymal tumors (PMT). Methods: Clinical data, histopathological and immunohistochemical features of 3 PMT cases at different cites from the First Affiliated Hospital of Wenzhou Medical University were analyzed retrospectively. Results: Blood phosphorus decreased significantly in 3 cases before operation, 1 case was accompanied by adult chondropathy and 3 cases returned to normal after operation. The tumor cells were spindle shaped, oval, arranged in bundle or braid, without obvious atypia ornuclear division. Abundant blood vessels, and smoke-like matrix could be found in the stroma. In some cases, mucoid, bone-like matrix and mature adipose tissues could be seen. The tumor cells expressed Bcl-2, CD56, CD99 and Satb2. Conclusion: Phosphaturia mesenchymal tumor is quite rare and its diagnosis should be based on histopathology, immunohistochemical markers and clinical data.
