YE Shanshan1, ZHANG Xu2, WU Senxiang1, CHEN Yuanyuan1,YANG Yanwei1
1.Department of Neurology, Wenzhou People’s Hospital, Wenzhou Third Clinical College of Wenzhou Medical University, Wenzhou 325000, China; 2.Department of Neurology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325015, China
YE Shanshan,ZHANG Xu,WU Senxiang, et al. Analysis of leukoaraiosis related risk factors[J]. JOURNAL OF WEZHOU MEDICAL UNIVERSITY, 2021, 51(8): 678-681.
Abstract：Objective: To analyze the risk factors of leukoaraiosis. Methods: A total of 188 inpatients were selected from the Department of Neurology, Wenzhou People’s Hospital from July 2019 to December 2020.According to the presence or absence of leukoaraiosis (LA), the patients were divided as case group (78 cases) and control group (110 cases). Age, gender, hypertension, diabetes, blood biochemical, and microalbuminuria indexes of both groups were collected. The univariate comparison was conducted in the data of the two groups,and multivariate logistic regression analysis was made of the significant factors in the univariate comparison.Results:Univariate analysis showed statistical difference (P<0.05) between the two groups, with the case group significantly higher positive rate of age, homocysteine, hypertension and microalbuminuria than the control group.Multivariate logistic regression analysis showed that age (OR=1.163, 95%CI=1.107-1.221),microalbuminuria (OR=2.599, 95%CI=1.132-5.966), and hypertension (OR=2.767, 95%CI=1.223-6.261) remain to be independent risk factors for leukoaraiosis. Conclusion: Age, microalbuminuria and hypertension were independently related to leukoaraiosis.
