Imaging diagnosis of eosinophilic granuloma of skull in children
1.Department of Radiology, People’s Hospital of Taishun, Wenzhou, 325500; 2.Department of Radiology, the Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325027
YE Shengli1,LIN Xiaohe1,LUO Lili1, et al. Imaging diagnosis of eosinophilic granuloma of skull in children[J]. JOURNAL OF WEZHOU MEDICAL UNIVERSITY, 2014, 44(10): 759-761.
Abstract：Objective: To investigate the image manifestation and improve the ability of diagnosis of skull eosinophilic granuloma in chidlren. Methods: Imaging data of skull eosinoplilic granuloma in children-retrospective analysis of 20 cases by X-ray, CT and MRI scan, included: 2 cases of X-ray, 20 cases of CT scan, 4 cases of MRI scan (including 2 cases of enhancement scanning). Results: Out of 20 cases, single lesion was found in 16 cases, and multiple lesions were found in 4 cases. There were totally 26 lesions in all 20 patients, temporal bone (n=13), frontal bone (n=7), occipital bone (n=4), parietal bone (n=2) were respectively being involved. The X-ray findings of 2 cases were clear, sharp edge of the circular hole shaped bone destruction. The CT scanning found 26 lesions, including 7 cases of osteolytic destruction, 19 cases of punched-out like bone defect, 21 cases of soft tissue mass. The MRI scanning revealed 4 cases of soft tissue mass adjacent to the osteodestructions. Compared with gray matter of the brain, MR showed isosignal intensity on T1WI and T2WI after intravenous injection of Gd-DTPA, the lesions showed enhanced remarkably. Conclusion: The CT and MR manifestations of children skull EG have certain characteristics. Combination of medical record may improve the diagnostic accuracy in the majority of cases. The MRI can accurately show the location, shape and extent of skull eosinophilic granuloma in children which is valuable in differential diagnosis of various causes.
