The value of neck enhanced CT in preoperative evaluation of patients with secondary hyperparathyroidism
MENG Jiao1, LI Xinhai2, CHEN Haolu1, SONG Chunyi3, LI Hua1.
1.Department of Nephrology, Sir RunRun Shaw Hospital Xiasha Campus, Zhejiang University School of Medicine, Hangzhou 310016, China;2.Department of Radiology, Sir Run Run Shaw Hospital Xiasha Campus, Zhejiang University School of Medicine,Hangzhou 310016, China; 3.Department of Head and Neck Surgery, Sir Run Run Shaw Hospital, ZhejiangUniversity School of Medicine, Hangzhou 310016, China
MENG Jiao,LI Xinhai,CHEN Haolu, et al. The value of neck enhanced CT in preoperative evaluation of patients with secondary hyperparathyroidism[J]. JOURNAL OF WEZHOU MEDICAL UNIVERSITY, 2021, 51(3): 215-219.
Abstract：Objective: To evaluate the value of neck enhanced CT in the diagnosis of secondary hyperparathyroidism (SHPT). Methods: The clinical data of 47 patients with SHPT who underwent the first parathyroidectomy (PTX) in Sir Run Run Shaw Hospital from January 2018 to October 2019 were reviewed. The differences in specificity and sensitivity of neck enhanced CT, color Doppler ultrasound and 99mTc-MIBI radionuclide imaging were tested using the pathological results as the gold standard. The correlation and consistency between the parathyroid size measured by neck enhanced CT and measurement of gross pathological specimens were also analyzed. Results: The sensitivity of neck enhanced CT, color Doppler ultrasound and 99mTc-MIBI radionuclide imaging was 99.40%, 63.10% and 54.70% respectively, and the specificity was 66.60%, 88.80% and 77.70%. The sensitivity of neck enhanced CT was better than either color Doppler ultrasound (P=0.001) or 99mTc-MIBI radionuclide imaging (P=0.006), while there was no significant difference in specificity (P>0.05). The parathyroid maximum diameter measured by the neck enhanced CT had high correlation (r=0.777, P<0.001) and consistency with the gross pathological specimens. Conclusion: Neck enhanced CT has high diagnastic value in the accurate location diagnosis and size of SHPT, thus it can improve the surgery accuracy of SHPT.
