An analysis of high-risk factors of venous thromboembolism in patients after cerebral hemorrhage and establishment of an early warning model
WANG Hongxia1, ZHANG Qixia2, LI Dongmei3, LI Jufang4
1.Nursing Department of the First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325015, China;2.Intensive Care Unit of the First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325015, China;3.Department of Neurosurgery, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325015, China; 4.College of Nursing, Wenzhou Medical University, Wenzhou 325035, China.
WANG Hongxia,ZHANG Qixia,LI Dongmei, et al. An analysis of high-risk factors of venous thromboembolism in patients after cerebral hemorrhage and establishment of an early warning model[J]. JOURNAL OF WEZHOU MEDICAL UNIVERSITY, 2021, 51(2): 128-132.
Abstract：Objective: To explore the high-risk factors of venous thrombo embolism (VTE) in patients after cerebral hemorrhage and to establish an early warning model to provide reference for the prevention and treatment of VTE. Methods: Totally 166 patients with VTE after neurosurgery cerebral hemorrhage in the First Affiliated Hospital of Wenzhou Medical University from January 2016 to June 2019 were randomly collected as the observation group, and 160 patients without VTE as the control group. Their general information as well as clinical and treatment data were collected, for an analysis of high-risk factors of VTE. An early warning model was established based on the summary results of the high-risk factors of VTE and the weight of the OR value. Results: The age, weight, and body mass index (BMI) of the observation group were higher than those of the control group (P<0.05). High risk factors for VTE in patients after cerebral hemorrhage: application of dehydrating agent (OR=8.889), bed time≥72 h (OR=7.091), muscle strength≤grade 3 (OR=1.515), central venous catheterization (OR=2.874), the application of hemostatic drugs (OR=2.946). The protective factors for VTE after cerebral hemorrhage included the application of preventive anticoagulants (OR=0.444). Compared with moderate to severe patients, light coma and conscious patients were not so easily inflicted by VTE (OR=0.138, 0.228). After the early warning model was established, the ROC curve proved it was effective. When the score was greater than 17.5 points, it was evaluated as high risk. Conclusion: The establishment of a risk warning model for VTE in patients after cerebral hemorrhage can detect high-risk patients in time so that preventive measures can be taken as soon as possible.
