MA Jun,GUAN Xueqiang. Correlation between osteocalcin and coronary artery disease: a cross-sectional study[J]. JOURNAL OF WEZHOU MEDICAL UNIVERSITY, 2020, 50(12): 998-1002.
Abstract：Objective: To investigate the relationship between osteocalcin (OC) and the angiographically demonstrated coronary artery disease (CAD). Methods: A total of 317 consecutive patients with stable chest pain suspected of CAD underwent elective coronary angiography (CAG). The association between OC and CAD was analyzed. Results: An inverse association was displayed between OC and CAD. Compared with lowest OC level,the highest OC level was related with lower CAD risk (P<0.01). After adjustment of traditional coronary risk factors, OC was an independent predictor of CAD (OR=0.93, 95%CI=0.90-0.96, P<0.01). Conclusion: Among older patients suspected of CAD, higher OC indicated an decreased CAD risk. OC was an independent predictor of CAD.
