HUANG Ying,SU Chunxia. The effect of delayed ICU transfer on the incidence of ventilator-associated pneumonia in patients with endotracheal intubation[J]. JOURNAL OF WEZHOU MEDICAL UNIVERSITY, 2020, 50(8): 674-676.
Abstract：Objective: To investigate the effect of delayed ICU transfer on the incidence of ventilator-associated pneumonia (VAP) in patients with endotracheal intubation. Methods: A total of 348 patients admitted to the ICU of Shanghai Pulmonary Hospital of Tongji University from June 2016 to June 2018 were enrolled in this study, who were divided into delayed group (n=87) and non-delayed group (n=261). The χ2 test was used to compare the incidence of VAP in the two groups. Logistic regression model was performed to study the effect of delayed ICU transfer on VAP. Results: The incidence of VAP in the delayed ICU group was significantly higher than that in the non-delayed group (χ2=21.426, P<0.001). Except for the delayed transfer to ICU, among the influencing factors of VAP, there were statistically significant differences between the groups in age, antibiotic history, enteral nutrition, and coma (P<0.05). After deducting the effect of gastrointestinal nutrition and conscious state, delayed ICU transfer was an independent risk factor for VAP compared with non-delayed ICU (OR=2.644, 95%CI=1.494-4.677, P=0.001). In addition, gastrointestinal nutrition (OR=3.419, 95%CI=1.980-5.905, P<0.001) and coma (OR=2.681, 95%CI=1.542-4.661, P<0.001) were also independent risk factors for VAP. Conclusion: Delayed ICU transfer could result in an increased incidence of VAP. Therefore, critically ill patients with endotracheal intubation should be provided with standardized VAP precautions as soon as possible before ICU transfer so as to reduce the occurrence of VAP.
