The association between functional liver volume and liver function evaluated by quantitative analysis of gadoxetic acid-enhanced magnetic resonance imaging
CAI Jiale1, WANG Zhaohong2, CHEN Hui2, TONG Hongfei2
1.School of Nursing, Wenzhou Medical University, Wenzhou 325035, China; 2.Department of Hepatobiliary Surgery, the Second Affiliated Hospital & Yuying Children’s Hospital of Wenzhou Medical University, Wenzhou 325027, China
CAI Jiale,WANG Zhaohong,CHEN Hui, et al. The association between functional liver volume and liver function evaluated by quantitative analysis of gadoxetic acid-enhanced magnetic resonance imaging[J]. JOURNAL OF WEZHOU MEDICAL UNIVERSITY, 2020, 50(8): 637-641.
Abstract：Objective: To compare correlations between FLV and Child-Pugh classification of liver function. Methods: All 25 patients with liver cirrhosis performed enhanced CT and Gd-EOB-DTPA-enhanced MRI were recruited in this study. The liver function of all cases was evaluated by Child-Pugh classification. The contrast enhancement ratio (CER) was analyzed by SIlh-SIlu/SIlu, and the volume of each liver segment measured by MI-3DVS. Then correlations between anatomical liver volume, functional liver volume and Child-Pugh classification of liver function analyzed. Results: Analyses showed that Child-Pugh classification of liver function was negatively correlated to the ALV (r=-0.792, P<0.001), with determination coefficient of curve fitting (R2=0.63); Child-Pugh classification of liver function was also negatively correlated with FLV (r=-0.911, P<0.001), determination coefficient of curve fitting (R2=0.80). Compared between the two analyzing methods of liver volume, FLV had more significant negative correlation with Child-Pugh classification of liver function. Conclusion: The FLV calculated by CER of Gd-EOB-DTPA-enhanced MRI combined with ALV from MI-3DVS could better reflect the liver function than ALV.
