Application value of multi-mode imaging examination based on CT and MRI in accurate diagnosis of multinodular and multicentric hepatocellular carcinoma before resection
CHEN Chunmiao, CHEN Weiyue, YANG Weibin, LIN Guihan, YE Weichuan, LU Chenying, HU Xianghua, JI Jiansong
Key Laboratory of Imaging Diagnosis and Minimally Invasive Intervention Research, Department of Radiology, Lishui Central Hospital, Lishui 323000, China
CHEN Chunmiao,CHEN Weiyue,YANG Weibin, et al. Application value of multi-mode imaging examination based on CT and MRI in accurate diagnosis of multinodular and multicentric hepatocellular carcinoma before resection[J]. JOURNAL OF WEZHOU MEDICAL UNIVERSITY, 2020, 50(7): 563-567.
Abstract：Objective: To explore the application value of CT combined with MRI in accurate diagnosis of clinical multinodular and multicentric hepatocellular carcinoma before resection. Methods: A total of 42 patients with clinically diagnosed hepatocellular carcinoma in Lishui Central Hospital from May 2014 to April 2018 were collected and analyzed retrospectively. All patients underwent surgical resection and were confirmed as multinodular lesions by CT and/or MRI scan within one month before resection, and all nodules were pathologically diagnosed as hepatocellular carcinoma after resection. The diagnostic effects of CT, MRI and CT combined with MRI in the diagnosis of hepatic nodules were then compared. Results: Of 42 patients were included in the study 31 males and 11 females, with an average age of 56.0±10.4 years, 110 lesions were detected by pathological diagnosis, including 76 lesions of hepatocellular carcinoma. 89 lesions were detected by CT alone (80.90%) and 106 lesions by MRI alone (96.36%), of which 64 lesions (84.21%) and 75 lesions (98.68%)were hepatocellular carcinoma (84.21%, 98.68%). A total of 108 lesions were detected by combined examination (98.18%), and all 76 lesions of hepatocellular carcinoma were detected. According to the analysis, the detection rate of hepatocellular carcinoma lesions examined by combined examination was higher than by CT alone or MRI alone (P<0.001). The sensitivity, specificity, accuracy, positive predictive value and negative predictive value of different examination methods were all correlated with the diameter of the tumor, the larger, the higher all the indicators. When the diameter was larger than 2 cm, the diagnostic accuracy of CT or MRI alone was consistent with that of pathological examination of liver cancer lesions. Conclusion: CT combined with MRI is better than single examination in the detection rate and diagnostic accuracy of hepatocellular carcinoma lesions and small lesions, and therefore has good clinical application value in the accurate diagnosis of multinodular and multicentric hepatocellular carcinoma before resection.
