CHI Hai hong,HUANG Zhaoxia,CHENG Jing, et al. Observation on effects of the small follicles puncture using Gn 7-9 days in vitro fertilization cycles[J]. JOURNAL OF WEZHOU MEDICAL UNIVERSITY, 2014, 44(9): 657-.
Abstract：Objective: To observe clinical outcome of the patients with excessive follicular development in controlling ovulation process treating with the small follicles puncture. Methods: Sixty-four infertile women in our center accepted IVF treatment during the period from April 2011 to April 2012 were analyzed retrospectively. All of them had excessive follicular development and had the tendency of ovarian hyperstimulation syndrome (OHSS). They were divided into two groups based on the their wills. The follicle puncture group (n=36) and control group (n=32). The general index, the laboratory and the clinical outcome of the two groups were compared. Results: There were no statistically significant differences in age, time of infertility, basal and the day of follicles puncture hormones level (P>0.05). The day of hCG serum level of estradiol (estrogen, E2) and the number of oocyte retrieved in follicle puncture group was obviously lower than that in control group (P<0.05). The rates of fertilization, cleavage, and clinical pregnancy in follicle puncture group was obviously higher than that in control group (P<0.05). The follicle puncture group had no severe ovarian hyperstimulation, but the severe OHSS occurred in 13 patients (13/32, 40.6%) of control group. Conclusion: The small follicle puncture can effectively reduce the incidence of OHSS and improve the outcome of IVF-ET cycles.
