Abstract：Objective: To investigate the risk factors of diabetic retinopathy (DR). Methods: The current study was conducted in patients with type 2 diabetes mellitus (DM) by means of handy sampling from July to October 2018 in one community of Yueqing County, Wenzhou, China. Face-to-face interview, routine laboratory tests and eye examinations were applied by professional investigators strictly following by the specific standard operation procedures (SOP) of the present study. Multivariable logistic regression models were performed to screen the potential influential factors of DR. Results: Among 406 type 2 DM patients aged 40 years and over, 177 (43.6%) were diagnosed as DR (107 with mild DR, 57 with moderate DR, and 13 with severe DR). As compared with their counterparts, the incidence rate of DR in participants with the duration of DM from 5 to 9 years would like to be significantly increased by 8% [OR=1.08, 95%CI=0.69-1.67, P=0.008]. Meanwhile, patients whose glycosylated hemoglobin A1c (HbA1c) over 6.5% would have additional 16% chance to develop DR (OR=1.16, 95%CI=0.65-2.06, P=0.002) compared with those with HbA1c less than 6.5%. Conclusion: DR screening should be conducted in type 2 DM patients, especially in those with type 2 DM for more than 5 years and with abnormal HbA1c.
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