XU Lixia,SU Aifang,ZHOU Xiaohong.. The value of small dose pituitrin in conservative laparoscopic surgery for ectopic pregnancy[J]. JOURNAL OF WEZHOU MEDICAL UNIVERSITY, 2019, 49(4): 294-297.
Abstract：Objective: To investigate the value of small dose of pituitrin administered in conservative laparoscopic surgery for ectopic pregnancy. Methods: A total of 124 patients who were confirmed with ectopic pregnancy and underwent laparoscopic tubal incision were reviewed retrospectively in Jinhua Maternal and Childcare Hospital. Sixty-three patients included in the study group received injection of 2 U pituitrin into mesosalpinx at the implantation site intraoperatively; Sixty-one patients in the control group underwent routine laparoscopic tubal incision without pituitrin injection during the operation. The operation time, intraoperative blood loss, postoperative persistent ectopic pregnancy rate, postoperative uterine fallopian tube angiography, postoperative pregnancy rate and postoperative ectopic pregnancy rate were observed. Results: The operation time of the study group was (47.0±7.5) min, significantly shorter than that in the control group [(58.7±7.9)min] (P<0.01). The intraoperative blood loss in the study group was (17.3±7.3)mL, significantly less than the control group [(41.0±9.1)mL] (P<0.01); the incidence of persistent ectopic pregnancy (1.5%) in the study group was lower than that of the control group (3.3%) (P<0.05); the postoperative fallopian tube patency rate (55.6%) was higher than the control group (34.4%) (P<0.05) and the pregnancy rate within 1 year after surgery was significantly higher in the study group (46.6%) than that in the control group (31.6%) (P<0.01), while the ectopic pregnancy rate in the study group (1.7%) was lower than that in the control group (7.0%) (P<0.05). Conclusion: Laparoscopic fallopian tube incision after small dose of pituitary vasopressin at the oviduct pregnancy site of the tubal pregnancy could significantly reduce intraoperative bleeding, reduce the incidence of persistent ectopic pregnancy, protect postoperative fallopian tube function and improve postoperative pregnancy rate.
