HUANG Hu,YU Beibei,ZHAO Yaping, et al. The value of sonohysterography combined with quantitative analysis of three-dimensional power Doppler imaging in the diagnosis of intrauterine lesions[J]. JOURNAL OF WEZHOU MEDICAL UNIVERSITY, 2019, 49(1): 47-51.
Abstract:Objective: To investigate the value of saline infusion sonohysterography (SIS) combined with quantitative analysis of three-dimensional power Doppler imaging (3D-PDI) in the differential diagnosis of intrauterine lesions. Methods: SIS and 3D-PDI were carried on 109 cases of married women with transvaginal ultrasonography (TVS) prompting intrauterine lesions. A quantitative analysis was made by VOCAL software and the pathological results were compared. Results: Of all the 109 patients, there were 40 cases of endometrial polyp, 48 cases of submucosal fibroid, 16 cases of intimal hyperplasia and 9 cases of blood clot. The accuracy rate, specificity and sensitivity of TVS combined with color Doppler flow imaging (CDFI) in diagnosis of endometrial polyp were 78%, 80%, 75% respectively, while those of SIS combined with 3D-PDI were 98%, 97%, 98% respectively. The differences in VI, FI and VFI between endometrial polyp group and submucosal fibroid group were significant (P<0.05). Conclusion: SIS can show clearly the intrauterine lesions while 3D-PDI can display the lesion types of perfusion and quantitative analysis is able to be performed. The combination of both procedures may significantly improve the sensitivity and specificity of intrauterine lesion diagnosis.
[1] 中国医师协会超声医师分会妇产学组. 妇科超声造影临床应用指南[J]. 中华医学超声杂志(电子版), 2015, 2(12): 94-98.
[2] 薛凯, 许锋, 杨大震, 等. 宫腔镜电切术治疗子宫黏膜下肌瘤300例临床分析[J]. 中国生育健康杂志, 2017, 28(4): 319-322.
[3] 赵旸, 李荣环, 王睿, 等. 绝经后子宫内膜息肉合并子宫内膜不典型增生及子宫内膜癌高危因素分析[J]. 中国妇产科临床杂志, 2012, 13(6): 422-425.
[4] DREISLER E, STAMPE S S, IBSEN P H, et a1. Prevalence of endometrial polyps and abnormal uterine bleeding in a Danish population aged 20-74 years[J]. Ultrasound Obstet Gynecol, 2009, 33(1): 102-108.
[5] PARKER W H. Etiology, symptomatology, and diagnosis of uterine myomas[J]. Fertil Steril, 2007, 87(4): 725-736.
[6] OKOLO S. Incidence, aetiology and epidemiology of uterine fibroids[J]. Best Pract Res Clin Obstet Gynaecol, 2008, 22(4): 571-588.
[7] OVSIENKO A B, GRADIL N P, BESTAEVA A E, et a1. Balneotherapy to the treatment of patients with hysteromy-oma[J]. Vopr Kurortol Fizioter Lech Fiz Kult, 2010(2): 25-26.
[8] 崔琪, 张屹辉, 俞红英, 等. 阴道超声联合改良宫腔声学造影诊断宫腔病变的价值[J]. 中国妇幼保健, 2017, 32(24): 6312-3614.
[9] GOLDSTEIN S R, MONTEAGUDO A, POPIOLEK D, et al.
Evaluation of endometrial polyps[J]. Am J Obstet Gynecol, 2002, 186(4): 669-674.
[10] 王雪, 黄雅南, 朱欢乐, 等. 子宫内膜息肉和I期子宫内膜癌的MRI特征分析[J]. 中华全科医学, 2015, 13(11): 1824-1827, 1907.
[11] 周凤英, 王砺聪, 张小田, 等. 弹性成像在评价子宫肌瘤性质中的应用价值[J]. 中国超声医学杂志, 2015, 31(2): 154-156.
[12] GALVAN R, MERCE L, JURADO M, et a1. Three-dimensional power doppler angiography in endometrial cancer: correlation with tumor characteristics[J]. Ultrasound Obstet Gynecol, 2010, 35(6): 723-729.
[13] 尹海辉, 赵雅萍, 何慧疗, 等. 三维能量多普勒定量超声对产前胎盘植入的诊断价值[J]. 医学研究杂志, 2015, 44(1): 76-79.
[14] BILGE O, CIHAN K, CIHAN I, et al. Diagnostic utility of saline infusion doppler sonohysterography in endometrial mass lesions[J]. Pak J Med Sci, 2016, 32(2): 284-288.
[15] DESSOLE S, RUBATTU G, FARINA M, et a1. Risks and usefulness of sonohysterography in patients with endometrial carcinoma[J]. Am J Obstet Gynecol, 2006, 194(2): 362-368.