YU Neng,FANG Lue,HUANG Xiaotao, et al. The effect of combined treatment of Chinese and western medicine on perioperative inflammation of fracture[J]. JOURNAL OF WEZHOU MEDICAL UNIVERSITY, 2018, 48(10): 764-768.
Abstract：Objective: To explore the clinical curative effect of combined traditional Chinese medicine and western medicine in the treatment of infection in perioperative period of fracture. Methods: A total of 80 patients with closed fractures of extremities (upper and lower limbs) in Cixi Traditional Chinese Medicine Hospital from October 2014 to March 2016 were included. They were divided into the control group (clinical routine medicine) and the observation group (traditional Chinese medicine combined with clinical routine medicine). For each group of patients, C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), white blood cell count (WBC), neutrophil (NEU) ratio, tumor necrosis factor-α (TNF-α), interleukin-1 (IL-1) and interleukin-6 (IL-6) were measured. Results: The CRP, ESR, WBC, NEU ratio, TNF-α, IL-1, IL-6 of the control group and observation group were the highest at 1 day after operation, then decreased at 5 days after operation, the difference was statistically significant (P<0.01). And the decrease of the observation group was more obvious. It was found in the late follow-up that there were 2 cases of infection in the control group and no infection patients in the observation group. Conclusion: The combined treatment of traditional Chinese medicine and Western medicine in perioperative period of fracture can decrease the inflammatory medium release, which may produce and added effect on the prevention of infection.
