WANG Xiaohua,HE Huiliao,JIANG Shuying, et al. The relationship between the shear wave velocities of gastric cancer tissues and clinical characteristics of gastric cancer patients[J]. JOURNAL OF WEZHOU MEDICAL UNIVERSITY, 2018, 48(9): 688-690,693.
Abstract： Objective: To investigate the relationship between the shear wave velocities of gastric cancer tissues and clinical characteristics in gastric cancer patients. Methods: A total of 53 patients with gastric cancer confirmed by operative pathology underwent an ultrasound-based acoustic radiation force impulse (ARFI) technique before the surgery. The shear wave velocity was obtained using virtual tough tissues quantification (VTQ) of ARFI technique, and the relationship between the findings of VTQ in gastric cancer tissues and clinical characteristics in gastric cancer patients were analyzed, including their sex and age, size of lesions, the tumor location, invasive depth, lymph node metastases, and degree of tissue differentiation. Results: The preoperative shear wave velocities of gastric cancer tissues were not correlated with sex and age of the patients or size and location of the tumor (P>0.05). There was no significant difference in the degree of tissue differentiation (P>0.05). The shear wave velocities of gastric cancer tissues in patients with lymph node metastases were higher than those in patients without lymph node metastases (P<0.05), and they were positively correlated with the depth of tumor invasion (P<0.05). Multiple linear regression analysis revealed lymph node metastases were related with the shear wave velocities of gastric cancer tissues. Conclusion: The shear wave velocities of gastric cancer tissues were positively related with lymph node metastases. It may be considered a helpful index in assessing gastric cancer and provide basis for the formulation of the therapeutic regimen of the gastric cancer patients.
