PAN Debiao,YE Guanxiong,WU Chengjun, et al. Prosthetic effect of recombinant human basic fibroblast growth factor combined with silvadene cream on the healing of chronic and refractory wound[J]. JOURNAL OF WEZHOU MEDICAL UNIVERSITY, 2014, 44(4): 294-296.
Abstract：Objective: To explore and discuss the therapeutic effect of chronic and refractory wound by recombinant human basic fibroblast growth factor combined with silvadene cream. Methods: Eighty cases with chronic and refractory wound were selected from Lishui People抯 Hospital between July 2008 and March 2013. These patients were randomly divided into 4 groups: group A receiving regular therapy, group B receiving recombinant human basic fibroblast growth factor, group C receiving silvadene cream, group D receiving recombinant human basic fibroblast growth factor combined with silvadene cream, 20 patients in each group. The wound healing period and the wound healing rates in the 4 groups were recorded. Results: As compared with group A, B, and C, the wound healing period was significantly decreased (P<0.05), the wound healing rate in day 7, 11, 14, 17, and 21 was obviously inereased (P<0.05). Conclusion: Recombinant human basic fibroblast growth factor combined with silvadene cream can promote the healing of chronic and refractory wound.
