磁敏感加权成像在脑部钙化和脑微出血诊断中的应用价值

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摘要目的：评估磁敏感加权成像（SWI）在发现和辨别脑部钙化和慢性微出血中的应用价值。方法：回顾性分析2013年10月至2016年10月温州医科大学附属舟山医院经CT、MRI确诊为脑部钙化（脑部钙化组）和微出血（脑微出血组）的100例患者的临床资料。MRI均行SWI序列扫描。由2位观察者分别对病灶进行定性和定量分析。结果：脑部钙化组50例患者共76个钙化灶，脑微出血组50例患者共245处微出血。SWI序列对钙化有良好的观察能力（k=0.7）。所有微出血在SWI序列都能观察到，但对成分评估只有中等程度的观察能力（k=0.5）。钙化和慢性微出血的平均像素值在相位SWI序列分别为（-312.5±187.5）SD和（541.9±301.7）SD，差异有统计学意义（P＜0.001）。结论：相位SWI在发现及鉴别脑部钙化和微出血方面可发挥重要作用。

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关键词 ：脑部钙化, 脑出血, 磁敏感加权成像

Abstract：Objective: To evaluate the clinical value of susceptibility weighted imaging (SWI) in the detection and differentiation of intracranial calcifications and chronic microbleeds. Methods: The clinical data of 100 patients with cerebral calcification or microhemorrhage in Wenzhou Medical University Affiliated Zhoushan Hospital from October 2013 to October 2016 were retrospectively analyzed. MRI scans were performed on SWI sequences. These lesions were centering and quantitatively analyzed by two observers. Results: There were 76 calcifications in 50 patients, and other 50 patients had 245 microbleeds. The SWI sequence found that calcification had good observation ability (k=0.7). All the chronic microbleeds were seen on SWI but there was only moderate inter observer agreeability in evaluation of signal on phase component (k=0.5). Average pixel values of calcifications and chronic microbleeds were (-312.5±187.5) SD and (541.9±301.7) SD on phase SWI, respectively (P<0.001). Conclusion: Phase SWI can play an important role in the detection of intracranial calcifications and chronic microbleeds.

Key words： cerebral calcification cerebral hemorrhage susceptibility weighted imaging

收稿日期: 2017-11-01

基金资助:浙江省医药卫生科研基金资助项目（2015KYA227）。

作者简介: 金美玉（1974-），女，吉林延边人，主治医师。

链接本文:

https://xb.wmu.edu.cn/CN/ 或 https://xb.wmu.edu.cn/CN/Y2018/V48/I6/454

[1] WU Z, MITTAL S, KISH K, et al. Identification of calcification with MRI using susceptibility-weighted imaging: A case study[J]. J Magn Reson Imaging, 2009, 29(1): 177-182.
[2] MAKARIOU E, PATLISALIDES A D. Intracranial calcifi-cations[J]. Appl Radiol, 2009, 38(11): 48-60.
[3] NUTE J L, ROUX L L, CHANDLER A G, et al. Differentiation of low attenuation intracranial hemorrhage and calcification using dual-energy computed tomography in a phantom system[J]. Invest Radiol, 2015, 50(1): 9-16.
[4] 衣慧灵, 刘兰祥, 齐曦明, 等. SPGR-T2*WI鉴别颅内出血和钙化的定量分析[J]. 放射学实践, 2013, 28(6): 623-627.
[5] 林一锱, 高源统, 严志汉. 磁敏感加权成像在早产儿颅内出血诊断中的应用价值[J]. 温州医科大学学报, 2015, 45 (8): 611-614.
[6] 刘孟辉, 刘建玲, 周志凌, 等. 定量磁敏感图在神经系统中的研究进展[J]. 国际医学放射学杂志, 2017, 40(3): 258-261.
[7] 兰振. 磁共振磁敏感加权成像在脑部疾病中的应用[J]. 实用医技杂志, 2016, 23(6): 613-614.
[8] SHAMS S, MARTOLA J, CAVALLIN L, et al. SWI or T2*: Which MRI sequence to use in the detection of cerebral microbleeds? The Karolinska Imaging dementia study[J]. AJNR Am J Neuroradiol, 2015, 36(6): 1089-1095.
[9] ZHU W Z, QI J P, ZHAN C J, et al. Magnetic resonance susceptibility weighted imaging in detecting intracranial calcification and hemorrhage[J]. Chin Med J (Engl), 2008, 121(20): 2021-2025.
[10] BARBOSA J H, SANTOS A C, SALMON C E. Susceptibility weighted imaging: Differentiating between calcification and hemosiderin[J]. Radiol Bras, 2015, 48(2): 93-100.
[11] CIRACI S, GUMUS K, DOGANAY S, et al. Diagnosis of intracranial calcification and hemorrhage in pediatric patients: Comparison of quantitative susceptibility mapping and phase images of susceptibility-weighted imaging[J]. Diagn Interv Imaging, 2017, 98(10): 707-714.
[12] ZULFIQAR M, DUMRONGPISUTIKUL N, INTRAPIROMKUL J, et al. Detection of intratumoural calcification in oligodendrogliomas by susceptibility-weighted MR imaging [J]. AJNR Am J Neuroradiol, 2012, 33(5): 858-864.